Pujalte 1994.
Methods | Allocation: "random allocation" ‐ no further details. Blindness: double ‐ placebo identical appearance to clonazepam solution. Duration: 2 weeks. | |
Participants | Diagnosis: schizophrenia and schizoaffective disorders (DSM‐III‐R) plus neuroleptic‐induced akathisa (Barnes Rating Scale for Drug‐Induced Akathisia). N=12. Age: mean ˜34 years. Sex: female 4, male 8. History: "acutely ill", duration of illness not specified. | |
Interventions | 1. Clonazepam: dose 0.5‐2.5mg/day. N=6. 2. Placebo. N=6. | |
Outcomes | Akathisia: Barnes Rating Scale for Drug‐Induced Akathisia, use of antiparkinsonian medicaton.
Adverse effects. Unable to use ‐ Akathisia: Barnes Rating Scale for Drug‐Induced Akathisia score (inexact p‐value). |
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Notes | Authors contacted for details on 17th March 2000. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |
EPRS ‐ Extra‐pyramidal symptom rating scale.