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Tear secretion as a function of duty cycle with chronically implanted stimulator. Rabbits received baseline (no transmitter), sham (transmitter held in place but no stimulation) and electrical stimulation (~2.8 mA, 170–680 μs pulses at 30 Hz) treatments. Duty cycle of 20% was implemented by 1 s of stimulation every 5 s, 50% by 1 s of stimulation every 2 s and 75% by 3 s of stimulation every 4 s. *p ≤ 0.05, compared to sham, and p < 0.01, compared to baseline, (n = 5).
