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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Radiat Res. 2019 Feb 4;191(4):311–322. doi: 10.1667/RR15240.1

FIG. 1.

FIG. 1

Directional genomic hybridization (dGH). Representative images of metaphase spreads labeled with dGH whole chromosome 1, 2 and 3 paints (red) and counter stained with DAPI (blue). Panel A: A normal metaphase spread free of any structural rearrangements. dGH chromosome paints uniformly label a single sister chromatid of a chromosome. Panel B: An inversion (double signal switch; yellow arrow) on chromosome 2. Panel C: Translocation involving chromosome 3 and a second, unpainted chromosome (white arrows).