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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Nat Rev Genet. 2018 Nov;19(11):718–732. doi: 10.1038/s41576-018-0052-8

Figure 3. Applications of DNA-based biological recorders.

Figure 3.

a | Use cases of DNA based recording (top) as well as applications across research and applied settings (bottom). b | Example utility of DNA-based recorders in the gut microbiome. Engineered cellular memory devices could be utilized for noninvasive multiplex temporal recording of important signals such as nutrient status and microbial- and host-derived metabolites. In addition, these recorders could mediate functional actions in response to specific signals or profiles of inputs. SCFA, short-chain fatty acids.