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Effect of IL‐1β, MK‐801, and MK‐801+IL‐1β on thermal hyperalgesia in rats. Paw withdrawal latency (PWL) was measured in rats given intrathecal saline (control, n=8), IL‐1β (IL, n=8), MK‐801 alone (MK, n=8), or MK‐801 at 1 h before IL‐1β (MK+IL, n=12). All values were normalized to the baseline (100%) and expressed as means±SEMs. *P<.05 relative to controls; #P<.05 relative to IL‐1β; †P<.05 relative to baseline
