Table 2.
ALFF differences between PD‐F, PD‐NF, and HCs groups
| Brain region (ALL) | Coordinates MNI | Clusters size (mm3) | T value | ||
|---|---|---|---|---|---|
| x | y | z | |||
| PD‐F versus PD‐NF | |||||
| Insula_L | −38 | 17 | 1 | 22 | 3.06 |
| Cingulum_Mid_R | 13 | −33 | 45 | 18 | 3.26 |
| Frontal_Mid_R | 46 | 32 | 35 | 17 | −2.61 |
| PD‐F versus HCs | |||||
| Frontal_Mid_L | −24 | 39 | 15 | 61 | 3.92 |
| Frontal_Mid_R | 30 | 48 | 9 | 204 | 6.24 |
| Supramarginal_L | −60 | −33 | 36 | 44 | 4.75 |
| Angular_L | −36 | −63 | 48 | 86 | 4.19 |
| Insula_L | −38 | 18 | 1 | 31 | 4.12 |
| PD‐NF versus HCs | |||||
| Frontal_Mid_R | 30 | 49 | 8 | 223 | 4.66 |
| Frontal_Mid_L | −30 | 51 | 15 | 46 | 3.31 |
| Angular_L | −39 | −75 | 46 | 89 | 3.92 |
| Occipital_Mid_L | −40 | −76 | 36 | 36 | 3.92 |
PD‐F, Parkinson's disease with fatigue; PD‐NF, Parkinson's disease without fatigue; HC, healthy control; AAL, anatomical automatic labeling; R, right; L, left; Sup, superior; Inf, inferior; Mid, middle; MNI, Montreal Neurological Institute; all the coordinates are denoted by MNI space coordinates (P < 0.05, AlphaSim corrected). T‐score denotes the statistic value of post hoc two‐sample t‐test after analysis of covariance between the three groups.