Skip to main content
. 2017 Feb 13;23(4):321–328. doi: 10.1111/cns.12676

Table 3.

Mean and standard deviation performance metrics for pre‐SCA3, SCA3 and control groups on the oculomotor parameters

Oculomotor signs Pre‐SCA3 SCA3 NC P Post hocs
Fixation stability
Frequency of SWJ (Hz) 0.54±0.47 0.79±0.56 0.06±0.13 <.0001 NC<Pre‐SCA3, SCA3
Average amplitude of SWJ (°) 1.15±0.77 1.53±0.93 0.23±0.43 <.0001 NC<Pre‐SCA3, SCA3
Gaze
Frequency of horizontal GEEM (Hz) 0.83±0.5 1.65±0.75 0.09±0.15 <.0001 SCA3>Pre‐SCA3>NC
Average amplitude of horizontal GEEM (°) 1.60±0.66 3.40±2.30 0.31±0.55 <.0001 SCA3>Pre‐SCA3>NC
Frequency of horizontal SWJ evoked by upward gaze (Hz) 0.63±0.52 1.03±0.70 0.07±0.15 <.0001 NC<Pre‐SCA3, SCA3
SPEM
Horizontal mean pursuit gain (%) 81.3±8.0 69.4±10.8 87.9±4.1 <.0001 NC, Pre‐SCA3>SCA3
Vertical mean pursuit gain (%) 64.4±18.2 67.8±15.4 81.8±4.5 .0003 NC>Pre‐SCA3, SCA3
Prosaccade
Upward saccade latency (milliseconds) 200±27.6 205±36.5 203±23.2 >.05 NC=Pre‐SCA3=SCA3
Horizontal peak saccade velocity (°/seconds) 529±66.0 527±130.3 524±56.9 >.05 NC=Pre‐SCA3=SCA3
Upward peak saccade velocity (°/seconds) 424±81.6 338±109.3 563±100.5 <.0001 SCA3<Pre‐SCA3<NC
Horizontal saccadic accuracy (%) 98.4±3.7 92.8±16.9 98.2±3.5 >.05 NC=Pre‐SCA3=SCA3
Upward saccadic accuracy (%) 93.0±9.0 85.1±16.0 94.4±7.4 .0135 SCA3<NC
Antisaccade
Total antisaccadic error rate (%) 36.4±24.1 66.8±22.9 19.2±14.0 <.0001 SCA3>Pre‐SCA3>NC

Pre‐SCA3, preclinical SCA3; SCA3, spinocerebellar ataxia type 3; NC, normal controls; SWJ, square‐wave jerk; GEEM, gaze‐evoked eye movement; SPEM, smooth pursuit eye movement.

Oculomotor parameters are given as mean±SD.