Table 4.
Correlations between oculomotor parameters and clinical data in SCA3
| CAG repeat length in expanded allele | Disease duration | SARA score | |
|---|---|---|---|
| Frequency of SWJ | NS | NS | 0.319* |
| Average amplitude of SWJ | NS | NS | 0.287* |
| Frequency of horizontal GEEM | NS | 0.550** | 0.593** |
| Average amplitude of horizontal GEEM | NS | 0.526** | 0.760** |
| Horizontal mean pursuit gain | NS | −0.470** | −0.642** |
| Vertical mean pursuit gain | NS | NS | −0.347** |
| Upward saccade latency | NS | 0.280* | 0.360** |
| Horizontal peak saccade velocity | NS | NS | −0.345** |
| Upward peak saccade velocity | NS | −0.282* | −0.397** |
| Horizontal saccadic accuracy | NS | −0.327* | −0.480** |
| Upward saccadic accuracy | NS | −0.471** | −0.547** |
| Total antisaccadic error rate | 0.330** | 0.360** | 0.533** |
| Age at onset of gait ataxia | −0.835** | NS | NS |
| SARA score | NS | 0.742** | NA |
SCA, spinocerebellar ataxia; SARA, Scale for the Assessment and Rating of Ataxia; SWJ, square‐wave jerk; GEEM, gaze evoked eye movement; SPEM, smooth pursuit eye movement; NS, not significant; NA, not available.
This study included both preclinical and manifest SCA3 together. Pearson correlation coefficients, two‐tailed are given.
*P<.05, **P<.01.