α‐M significantly decreased Aβ40, Aβ42 levels in primary cortical neurons. Aβ40 (A), Aβ42 (B), and sAPPα (C) levels were detected in supernatant from cultured cortical neurons incubated with various concentration of α‐M for 24 h. Data represent mean±SEM from at least three independent experiments performed in triplicate. *P<.05, **P<.01, compared with 0 nmol·L−1 of α‐M