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Effect of acute Asenapine on manic‐like behaviors. Effect of acute Asenapine (0.01 or 0.03 mg/kg, s.c.) administration on the locomotor activity of control and REM sleep deprived (SD) animals. Values plotted are mean ± SEM. ***P<.001 vs saline; + P=.052, #P=.001 vs SD‐saline, using two‐way ANOVA followed by Fisher PLSD post hoc test
