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. 2016 Feb 4;22(4):280–290. doi: 10.1111/cns.12494

Table 4.

Staining Scores of TRPV4‐, PKC‐, PKA‐Immunopositive Cells in FCD and Control Specimens

CTX (n = 10) FCDIa (n = 15) FCDIIa (n = 12) FCDIIb (n = 12)
TRPV4 1.15 ± 0.18 1.90 ± 0.14* 2.45 ± 0.25* 2.65 ± 0.33*
PKC 1.07 ± 0.12 1.36 ± 0.27* 2.21 ± 0.18* 2.57 ± 0.22*
PKA 1.51 ± 0.31 1.55 ± 0.37# 1.52 ± 0.29# 1.54 ± 0.24#

CTX, normal control cerebral cortex; FCD, focal cortical dysplasia; TRPV4, transient receptor potential vanilloid 4; PKC, protein kinase C; PKA, protein kinase A.

Data are expressed as mean ± SEM where immunoreactivity was scored as: 0, absent; 1, weak; 2, moderate; or 3, strong.

*P < 0.01, # P > 0.05, FCDIa, FCDIIa, FCDIIb versus CTX, ANOVA.