Table 4.
CTX (n = 10) | FCDIa (n = 15) | FCDIIa (n = 12) | FCDIIb (n = 12) | |
---|---|---|---|---|
TRPV4 | 1.15 ± 0.18 | 1.90 ± 0.14* | 2.45 ± 0.25* | 2.65 ± 0.33* |
PKC | 1.07 ± 0.12 | 1.36 ± 0.27* | 2.21 ± 0.18* | 2.57 ± 0.22* |
PKA | 1.51 ± 0.31 | 1.55 ± 0.37# | 1.52 ± 0.29# | 1.54 ± 0.24# |
CTX, normal control cerebral cortex; FCD, focal cortical dysplasia; TRPV4, transient receptor potential vanilloid 4; PKC, protein kinase C; PKA, protein kinase A.
Data are expressed as mean ± SEM where immunoreactivity was scored as: 0, absent; 1, weak; 2, moderate; or 3, strong.
*P < 0.01, # P > 0.05, FCDIa, FCDIIa, FCDIIb versus CTX, ANOVA.