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. 2016 Feb 28;22(6):507–517. doi: 10.1111/cns.12525

Figure 6.

Figure 6

VEGF Mediated the Increase of BMVECs Capillary‐like Tube Formation, Proliferation, and Migration by MiR‐150 Inhibitor. (A–B) VEGF‐neutralizing antibody significantly reversed miR‐150 downregulation induced increase of capillary‐like tube formation. The representative pictures of tube formation were shown, and the length of tube formation was measured. Bar = 100 μm. *P < 0.05 vs. the inhibitor control group, # P < 0.05 vs. the miR‐150 inhibitor. (C–D) VEGF‐neutralizing antibody significantly reversed miR‐150 downregulation induced increase of Ki‐67‐positive staining proportion of BMVECs. Pink for Ki‐67, blue for DAPI, Bar = 20 μm. *P < 0.05 vs. the inhibitor control group, # P < 0.05 vs. the miR‐150 inhibitor. (E–F) VEGF‐neutralizing antibody significantly reversed miR‐150 downregulation induced increase of migration distance of BMVECs. Bar = 25 μm. *P < 0.05 vs. the inhibitor control group, # P < 0.05 vs. the miR‐150 inhibitor.