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. 2016 Jan 27;22(3):220–229. doi: 10.1111/cns.12495

Figure 2.

Figure 2

Effect of ST09 on the Morris water maze performance of rats. (A) Escape latency to find the visible platform. (B) Swimming speed in visible platform trials. There was no difference among ST09 (1.73 mg/kg: n = 8, 3.46 mg/kg: n = 9, 6.92 mg/kg: n = 9), Donepezil (Don, n = 9), sham (n = 9), and 2‐VO (n = 9) in escape latency (A) and speed (B), indicating that rats in all these groups have similar motor and visual capabilities. (C) Escape latency to find the hidden platform on days 1–4 (two‐way repeated‐measures ANOVA, followed by Turkey post hoc test). (D–F) Swimming speed (D) and time (E) and distance (F) in the target zone in the spatial probe test. (G) Swimming trace in the spatial probe test. The smaller cycle represents the platform, and the larger cycle represents the pool edge (ST09: 3.46 mg/kg). Data are presented as mean ± SEM. in all panels. *P < 0.05, **P < 0.01 vs. sham; # P < 0.05, ## P < 0.01 vs. 2‐VO by one‐way ANOVA followed by LSD multiple comparisons post hoc tests.