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FDG‐PET. (A–B) Effect of ST09 on the glucose metabolism in VaD rats. Values are means ± SEM. n = 5. **P < 0.01 vs. sham, #
P < 0.05, ##
P < 0.01 vs. 2‐VO by one‐way ANOVA, followed by LSD multiple comparisons post hoc tests. (C) The GSH depletion by intra‐cerebroventricular injection BSO. (D–E) Effect of BSO on glucose metabolism in rats. Values are means of control ± SEM. n = 5. *P < 0.05, **P < 0.01 vs. control by one‐way ANOVA, followed by LSD multiple comparisons post hoc tests. (F) Pathways of ischemic vascular dementia and possible multifunctional therapeutic mechanisms of ST09.