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. 2019 Mar 30;8(6):e1586042. doi: 10.1080/2162402X.2019.1586042

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Functional enrichment analysis of the primary and PDX samples. a) Correlation plot of the ssGSEA normalized enrichment scores (NES) across the samples. b) Heatmap representing the top and bottom enriched pathways scored by ssGSEA. c) Barplot showing the expression of HLA molecules (HLA-A, HLA-B and HLA-C) across the samples. d) 3D scatter plot of the expression levels of 110 TAP-related genes showing strong correlation across samples. e) Heatmap showing the correlation coefficient of the TAP processing genes across all samples.