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. 2019 Mar 28;8(6):e1593811. doi: 10.1080/2162402X.2019.1593811

Figure 1.

Figure 1.

Schematic representation of immune and inflammatory mediators selected and categorized by immune response type.

A literature search was conducted to identify secreted immune mediators associated with different categories of immune activation with known possible roles in cancer immunity. This identified 44 immune mediator markers (cytokines, chemokines, soluble inflammation and angiogenic factors), categorized into the following groups: Th1, Th2, Th9, Th17, M1 macrophage, M2 macrophage, anti-parasitic/infection response (immune activation genes, in orange), and, angiogenesis and inflammation (in blue) for evaluation of associations with patient survival in ovarian carcinoma.