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. 2019 Mar 1;8(5):e1581529. doi: 10.1080/2162402X.2019.1581529

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 5. — Correlation PD-L1 expression and the expression of c-Myc target genes in PDAC. (a) Positive correlation between the expression of c-Myc and the expression of CD274 in 177 individual human PDAC specimens. (b–e) Positive correlation between the expression of c-Myc-target genes [ST3GAL3 (b), BRCA1 (c), SOCS3 (d) and CCNG2 (e)] and CD274 expression in 177 human PDAC samples. (f–g) Inverse correlation between MYCN expression and c-Myc/CD274 expression in 177 human PDAC samples. (h) OS in 177 PDAC patients with high (blue line) or low (yellow line) c-Myc-expressing tumors. (i) OS in 177 PDAC patients with high (blue line) or low (yellow line) CD274-expressing tumors. P-values were calculated by performing a Log-rank test.