Table 1.

Patient’s characteristics and VISTA expression results on test-cohort (n = 165). Total patient´s numbers do not add to n = 165 due to missing analysable tumor spots on the multi-spot TMA.

			VISTA expression surface margin					VISTA expression infiltration margin
			low		high			low			high
sex	No	%	No	%	No	%	p value	No	%	No	%	p value
female	16	9.7%	13	81.3%	3	18.8%		11	73.3%	4	26.7%
male	149	90.3%	110	77.5%	32	22.5%	0.508	104	72.2%	39	27.3%	0.614
age group
<65 years	72	43.9%	55	78.6%	15	21.4%		51	73.9%	18	26.1%
>65 years	92	56.1%	67	77.0%	20	23.0%	0.485	63	71.6%	25	28.4%	0.444
tumor stage
pT1	49	30.1%	28	60.9%	18	39.1%		29	63.0%	17	37.0%
pT2	29	17.8%	18	62.1%	11	37.9%		20	69.0%	9	31.0%
pT3	84	51.5%	76	93.8%	5	6.2%		65	80.2%	16	19.8%
pT4	1	0.6%	0	0.0%	1	100%	<0.0001	0	0.0%	1	100%	0.062
lymph node metastasis
pN0	63	38.7%	34	56.7%	26	43.4%		35	59.3%	24	40.7%
pN1	72	44.2%	65	92.9%	6	7.1%		57	81.4%	13	18.6%
pN2	13	8%	10	83.3%	2	16.7%		11	84.4%	2	15.4%
pN3	15	9.2%	13	86.7%	2	13.3%	<0.0001	11	73.3%	4	26.4%	0.030
UICC stage
I	41	26.1%	21	51.2%	20	48.8%		23	57.6%	17	42.5%
II	21	13.4%	15	71.4%	6	28.6%		14	66.7%	7	33.3%
III	75	47.8%	69	92.0%	6	8.0%		60	78.9%	16	21.1%
IV	20	12.7%	17	85.9%	3	15.0%	<0.0001	17	85.0%	3	15.0%	0.045