Table 3.
Cox multivariate survival analysis assessing the impact of different cancer subtypes on mortality of systemic sclerosis patients. Abbreviations: CI (confidence interval); CNS (central nervous system); HR (hazard ratio).
| Cancer | HR | 95%CI | p-value |
|---|---|---|---|
| CNS cancer | 2.86 | 1.62 to 5.05 | 0.0003 |
| Oropharynx cancer | 0.93 | 0.38 to 2.24 | 0.8665 |
| Thyroid cancer | 1.14 | 0.70 to 1.87 | 0.5979 |
| Larynx cancer | 2.39 | 1.28 to 4.47 | 0.0064 |
| Sarcoma | 1.43 | 0.81 to 2.52 | 0.2223 |
| Melanoma | 1.18 | 0.77 to 1.79 | 0.4502 |
| Breast cancer | 1.75 | 1.48 to 2.06 | <0.0001 |
| Lung cancer | 4.59 | 3.66 to 5.77 | <0.0001 |
| Oesophagus cancer | 3.62 | 1.88 to 6.99 | 0.0001 |
| Stomach cancer | 3.42 | 2.30 to 5.08 | <0.0001 |
| Liver cancer | 5.30 | 3.37 to 8.34 | <0.0001 |
| Pancreas cancer | 5.87 | 4.23 to 8.14 | <0.0001 |
| Colorectal cancer | 1.63 | 1.31 to 2.02 | <0.0001 |
| Kidney cancer | 1.97 | 1.35 to 2.87 | 0.0004 |
| Bladder cancer | 2.27 | 1.71 to 3.03 | <0.0001 |
| Prostate cancer | 0.92 | 0.58 to 1.46 | 0.7272 |
| Ovarian cancer | 2.67 | 1.92 to 3.80 | <0.0001 |
| Uterus cancer | 1.61 | 1.13 to 2.28 | 0.0081 |
| Cancer of the cervix uteri | 1.85 | 1.05 to 3.26 | 0.0346 |
| Vagina and vulva cancer | 3.23 | 1.97 to 5.31 | <0.0001 |
| Acute leukemia | 1.53 | 0.97 to 2.40 | 0.0667 |
| Chronic leukemia | 2.09 | 1.21 to 3.61 | 0.0083 |
| Hodgkin’s lymphoma | 3.72 | 2.23 to 6.21 | <0.0001 |
| Non-Hodgkin’s lymphoma | 2.20 | 1.64 to 2.96 | <0.0001 |
| Multiple myeloma | 3.56 | 2.31 to 5.48 | <0.0001 |
| Myelodysplastic syndrome | 2.48 | 0.93 to 6.63 | 0.0709 |
| Cancer of unknown primary | 1.65 | 1.27 to 2.13 | 0.0001 |
| Other neoplasms | 3.14 | 2.33 to 4.23 | <0.0001 |