Table 2.
Baseline demographics, risk factors, and clinical measures by HRQOL category
| All (N = 5104) | Poor HRQOLa (N = 294) | Good HRQOL (N = 4810) | P | |
|---|---|---|---|---|
| Age (year), mean (SD) | 62.6 ± 10.7 | 65.2 ± 11.0 | 62.4 ± 10.7 | <0.001 |
| Female sex, n (%) | 1728 (33.9) | 117 (39.8) | 1611 (33.5) | 0.03 |
| Han ethnic, n (%) | 5034 (98.6) | 290 (98.6) | 4744 (98.6) | 1.00 |
| Body mass index, mean (SD) | 24.7 ± 3.0 | 24.8 ± 3.1 | 24.7 ± 3.0 | 0.18 |
| Vascular risk factors, n (%) | ||||
| Ischemic stroke | 1018 (20.0) | 56 (19.0) | 962 (20.0) | 0.69 |
| TIA | 172 (3.4) | 10 (3.4) | 162 (3.4) | 0.98 |
| Myocardial infarction | 92 (1.8) | 6 (2.0) | 86 (1.8) | 0.75 |
| Congestive heart failure | 77 (1.5) | 7 (2.4) | 70 (1.5) | 0.31 |
| Known atrial fibrillation or flutter | 173 (3.4) | 10 (3.4) | 163 (3.4) | 0.99 |
| Hypertension | 3358 (65.8) | 219 (74.5) | 3139 (65.3) | 0.001 |
| Diabetes mellitus | 1083 (21.2) | 82 (27.9) | 1001 (20.8) | 0.004 |
| Dyslipidemia | 560 (11.0) | 34 (11.6) | 526 (10.9) | 0.74 |
| Current or previous smoking | 2191 (42.9) | 106 (36.1) | 2085 (43.3) | 0.01 |
| Alcohol consumption | 1582 (31.0) | 85 (28.9) | 1497 (31.1) | 0.43 |
| Index event, n (%) | ||||
| Minor stroke | 3677 (72.0) | 249 (84.7) | 3428 (71.3) | <0.001 |
| TIA | 1427 (28.0) | 45 (15.3) | 1382 (28.7) | |
| Premorbid mRS, n (%) | ||||
| 0 | 4212 (82.5) | 249 (84.7) | 3963 (82.4) | 0.30 |
| 1 | 757 (14.8) | 39 (13.3) | 718 (14.9) | |
| 2 | 135 (2.6) | 6 (2.0) | 129 (2.7) | |
| NIHSS at baseline, median (IQR) | 2 (0–2) | 2 (1–3) | 1 (0–2) | <0.001 |
| In‐hospital treatment, n (%) | ||||
| Antihypertensive | 1450 (28.4) | 17 (5.8) | 1433 (29.8) | <0.001 |
| Hypoglycemic | 520 (10.2) | 6 (2.0) | 514 (10.7) | <0.001 |
| Lipid‐lowering | 1824 (35.7) | 22 (7.5) | 1802 (37.5) | <0.001 |
| Dual antiplatelet | 2550 (50.0) | 129 (43.9) | 2421 (50.3) | 0.03 |
HRQOL, Health‐related quality of life; SD, standard deviation; IQR, interquartile range; mRS, modified Rankin score; NIHSS, National Institutes of Health stroke scale; TIA, transient ischemic attack. aPoor HRQOL defined as EQ‐5D index score of 0.5 or less using the Chinese preference weights. Comparison by chi‐square test for categorical and t‐test or Mann–Whitney U‐test for continuous variables.