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Opening KATP channels suppresses inflammasome activation and production of interleukin‐1beta (IL‐1β) induced by oxygen–glucose deprivation (OGD). (A) Represented immunoblots of NLRP3, cleaved Caspase‐1, and IL‐1β. Western blotting analyses of NLRP3 (B), cleaved Caspase‐1 (C), and maturation of IL‐1β (D). *P < 0.05, **P < 0.01 versus lane 1; #P < 0.05, ##P < 0.01 versus lane 4. Results are shown as mean ± SEM in every four individual experiments.
