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. 2014 Apr 8;20(6):528–538. doi: 10.1111/cns.12266

Figure 5.

Figure 5

Mdivi‐1 protected the animal from ischemic damage. (A) Control (sham‐operated) or MCAO mice (n = 7 to 8 mice in each group) were treated with different doses of Mdivi‐1 and infarct volume was assessed. (B) Sham or MCAO mice (n = 7 to 8 mice in each group) were treated with different doses of Mdivi‐1 and neurological score was assessed. (C) Sham or MCAO mice (n = 6 to 9 mice in each group) were treated with different doses of Mdivi‐1 and blood–brain barrier integrity was assessed with Evans blue staining. (D) Sham or MCAO mice (n = 6 to 9 mice in each group) were treated with different doses of Mdivi‐1 and brain water was assessed. All data are mean ± SD. *P < 0.05 compared with vehicle‐treated control.