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. 2014 Aug 21;20(11):973–981. doi: 10.1111/cns.12315

Figure 3.

Figure 3

Decreased numbers of CD4 and CD8 positive cells in gilz KO compared with WT in spinal cord after SCI. CD4 expression in spinal cord after SCI. Immunohistochemical analyses show that the number of CD4+ lymphocytes in perilesional area of spinal cord is reduced in gilz KO SCI compared with WT SCI mice. Scale bars 100 μm, 20X. CD4 staining: (A) Sham WT; (B) Sham gilz KO; (C) WT SCI; (D) gilz KO SCI. CD8 staining: (E) Sham WT; (F) Sham gilz KO; (G) WT SCI; and (H) gilz KO SCI. In the bottom graph is represented the densitometric analysis to quantify and highlight significant differences among experimental groups. For each staining, results are expressed as “% of positive staining” calculated on the mean of at least n = 3 acquired IHC image/group. **P < 0.005, ****P < 0.0001, Bonferroni test.