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. 2015 Oct 28;21(12):953–961. doi: 10.1111/cns.12472

Figure 4.

Figure 4

B7C efficiently inhibits Aβ1‐40‐induced apoptosis in SH‐SY5Y cells. (A) B7C (0.1–10 μM) was incubated with Aβ monomers for 6 days or preformed Aβ fibrils for 3 days and then added into SH‐SY5Y cells. Forty‐eight h after treatment, cell morphology was observed by the Nikon fluorescence microscopy. Scale bar = 50 μm. (B) Apoptosis was examined by counting the condensed nuclear stained by Hoechst 33342 from 4 randomly chosen fields. **P < 0.01, compared to control group. ## P < 0.01, compared to Aβ group.