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. 2015 Oct 28;21(12):953–961. doi: 10.1111/cns.12472

Figure 5.

Figure 5

B7C substantially decreases Aβ1‐40‐induced intracellular accumulation of ROS in SH‐SY5Y cells. (A) B7C (0.1–10 μM) was incubated with Aβ monomers for 6 days or preformed Aβ fibrils for 3 days and then added into SH‐SY5Y cells. Forty‐eight h after treatment, cells were incubated for 30 min at 37°C with DCFH‐DA (10 μM) in FBS‐free medium, washed twice with PBS, and then observed under the Nikon fluorescence microscope. Scale bar = 100 μm. (B) The DCF fluorescence intensity values were analyzed from 4 randomly chosen fields. **P < 0.01, compared to control group. ## P < 0.01, compared to Aβ group.