NaHS facilitates pentylenetetrazole (PTZ)‐ and pilocarpine‐induced epilepsy in rat. (A) The seizure severity was increased in NaHS‐treated group than in thecontrol group, especially for the seizure induced by 30 mg/kg and 75 mg/kg PTZ (n = 8, Mann–Whitney rank sum test, *P < 0.05, **P < 0.01). (B) The seizure latency was shortened in NaHS‐treated group (control: n = 4, NaHS: n = 6, unpaired t‐test, P < 0.01). (C) The seizure duration was prolonged in NaHS‐treated group (control: n = 4, NaHS: n = 6, unpaired t‐test, P < 0.01). (D) The seizure severity was increased in NaHS‐treated group than in the control group, especially for the seizure induced by 50 mg/kg pilocarpine (n = 8, Mann–Whitney rank sum test, *P < 0.05). (E) The seizure latency was not changed in NaHS‐treated group (n = 4, unpaired t‐test). (F) The seizure duration was prolonged in NaHS‐treated group (n = 4, unpaired t‐test, P < 0.05).