Sildenafil improved neuronal function through upregulation of BDNF/TrkB (A, C, D), NGF/TrkA (B, C, E) in the ischemic brain. Scale bar = 50 μm for TrkB (cortex and striatum), TrkA (cortex). Scale bar = 500 μm for TrkA (striatum). #
P < 0.05, ##
P < 0.01, ###
P < 0.001 compared with the sham‐operated group, *P < 0.05, **P < 0.01, ***P < 0.001 compared with the middle cerebral artery occlusion (MCAO) group.