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. 2019 Apr 24;41(1):284–293. doi: 10.1080/0886022X.2019.1597736

Table 2.

Effects of comorbidities and medications on log-NLR.

  + p-value
Male gender (M+,W-) 0.405 ± 0.214 0.385 ± 0.226 0.654
Comorbidity      
 Hypertension 0.417 ± 0.211 0.333 ± 0.234 0.102
 Diabetes mellitus 0.453 ± 0.221 0.353 ± 0.208 0.024
 Dyslipidemia 0.372 ± 0.201 0.420 ± 0.233 0.280
 Heart failure 0.452 ± 0.177 0.384 ± 0.226 0.234
 Angina pectoris 0.389 ± 0.179 0.399 ± 0.231 0.839
 Old myocardial infarction 0.406 ± 0.222 0.394 ± 0.218 0.824
 History of PCI 0.420 ± 0.194 0.391 ± 0.225 0.602
 Cerebral infarction 0.548 ± 0.242 0.374 ± 0.207 0.007
 Cerebral hemorrhage 0.564 ± 0.188 0.393 ± 0.218 0.276
 Peripheral artery disease 0.536 ± 0.217 0.352 ± 0.200 <0.001
 History of gastroduodenal ulcer 0.459 ± 0.234 0.392 ± 0.218 0.439
 Reflux esophagitis 0.466 ± 0.179 0.390 ± 0.222 0.320
Medications      
 ARB 0.400 ± 0.194 0.394 ± 0.244 0.894
 Diuretic agents 0.490 ± 0.211 0.351 ± 0.209 0.003
 ACEI 0.531 ± 0.213 0.380 ± 0.214 0.030
 Calcium channel blockers 0.436 ± 0.195 0.362 ± 0.234 0.095
 β-blockers 0.389 ± 0.171 0.402 ± 0.245 0.770
 Antiplatelet agents 0.426 ± 0.242 0.364 ± 0.190 0.166
 Warfarin 0.426 ± 0.176 0.392 ± 0.225 0.605
 PPI 0.415 ± 0.203 0.389 ± 0.226 0.584
 H2-blockers 0.425 ± 0.241 0.392 ± 0.215 0.593
 Statins 0.403 ± 0.201 0.394 ± 0.227 0.862
 Uric acid-lowering agents 0.436 ± 0.249 0.394 ± 0.217 0.622
 Oral hypoglycemic agents 0.420 ± 0.237 0.391 ± 0.215 0.603
 Insulin 0.733 ± 0.094 0.386 ± 0.213 0.006

Data given as mean ± SD or n (%). Differences in continuous variables between two groups were assessed using unpaired Student’s t-test.

ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; H2-blocker: histamine type 2 receptor blocker; log-NLR: log-transformed neutrophil/lymphocyte ratio; PCI: percutaneous coronary intervention; PPI: proton pump inhibitor.