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. 2019 Apr 19;7(1):1600939. doi: 10.1080/20016689.2019.1600939

Table 7.

Overview on academic phase III/IV ATMP clinical trials (Stem cell transplantation for haematological malignancies not included).

Trial Identifier Phase Sponsor Product/Procedure Indication
NCT00434616 III Franziskus-Krankenhaus Autologous bone marrow cells Critical limb ischemia
NCT01803347 III Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz Autologous expanded adipose-derived stem cells Anal fistula
NCT01569178 III Queen Mary University of London Bone marrow derived mononuclear cells Acute myocardia infarction
NCT03477500 III NCT03477500 Haukeland University Hospital Autologous stem cells Multiple sclerosis
ISRCTN54371254 III EBMT Central Office Autologous hematopoietic stem cells Diffuse cutaneous systemic sclerosis
EUDRACT2015-000431–32 III Universidad Autónoma de Madrid (U.A.M.) Autologous human bone marrow-derived expanded mesenchymal stromal cells Diaphyseal metaphyseal fracture and non union
n/a III Unknown Renal cell tumor vaccine Renal carcinoma
NCT00297193 III European Group for Blood and Marrow Transplantation | The Broad Foundation Autologous Stem Cells Cohn’s Disease
NCT02437708 III Universitaire Ziekenhuizen Leuven Stem cells Periapical bone healing in infected immature primary teeth
NCT01818310 II|III University Hospital Ostrava|Ministry of Health, Czech Republic|Regional Council of the Moravian-Silesian region, KU MSK Autologous Bone Marrow Aspirate Concentrate No-Option Critical Limb Ischemia
NCT02849613 II|III University Hospital, Grenoble Regenerative Stem Cell Therapy Stroke
NCT00904501 III CHU de Reims |Etablissement Francais du Sang Bone Marrow Autograft Limb Ischemia
NCT03325504 III Universidad Autonoma de Madrid Mesenchymal stem cells + Biomaterial Bone Healing in Non-Union
NCT01489501 III CellSeed France S.A.R.L.|FGK Clinical Research GmbH Oral mucosal epithelial cell sheet Limbal Stem Cell Deficiency
NCT00938847 III Asklepios proresearch Cordis Corporation Bone Marrow Derived Mononuclear Myocardial Regeneration
NCT01983748 III University Hospital Erlangen Dendritic Cells Plus Autologous Tumor RNA Uveal Melanoma
NCT01693042 II|III Johann Wolfgang Goethe University Hospital Autologous Bone Marrow-derived Mononuclear Cells Chronic Post-infarction Heart Failure
NCT01753440 II|III AHEPA University Hospital Allogeneic Stem Cells Implantation Combined With Coronary Bypass Grafting Ischemic Cardiomyopathy
NCT01759212 II|III AHEPA University Hospital Left Ventricular Assist Device + Allogeneic Mesenchymal Stem Cells Implantation End-stage Heart Failure
NCT03112122 IV Istituto Ortopedico Rizzoli Bone Marrow Concentrate Bone Marrow Edema
NCT03110679 IV Istituto Ortopedico Rizzoli Autologous Bone Marrow Concentrate Osteoarthritis
NCT02454231 II|III University of Florence|Tuscany Region Stem Cells Life Threatening Limbs Arteriopathy
NCT00539266 II|III Leiden University Medical Centre Autologous Bone Marrow-derived Mononuclear Cells Limb Ischemia
NCT03042572 II|III The Netherlands Organisation for Health Research and Development|UMC Utrecht Allogeneic Mesenchymal Stromal Cells No-option Ischemic Limbs
NCT01343836 II|III Erasmus Medical Center Autologous Tenocyte Implantation Chronic Achilles Tendinopathy
NCT03229564 II|III University of Zurich|ETH Zurich (Switzerland)|Julius Clinical, The Netherlands Autologous Dermo-epidermal Skin Substitute Treatment of Burns in Children
NCT02323620 III American Heart of Poland Bone marrow derived mononuclear cells Myocardial infarction
NCT03404063 II|III John Paul II Hospital, Krakow|KCRI|National Center for Research and Development, Poland CardioCell (Wharton´s Jelly derived mesenchymal stem cells) Acute Myocardial Infarction
NCT03423732 II|III John Paul II Hospital, Krakow|KCRI|National Center for Research and Development, Poland CardioCell (Wharton´s Jelly derived mesenchymal stem cells) No-option Critical Limb Ischemia
NCT02248532 II|III University Medical Centre Ljubljana CD34+ Cells Dilated Cardiomyopathy
NCT02144987 IV Instituto Valenciano de Infertilidad, IVI VALENCIA Bone Marrow Stem Cells Asherman’s Syndrome and Endometrial Atrophy
NCT03535480 IV Instituto de Investigacion Sanitaria La Fe Autologous Bone Marrow Stem Cells Premature Ovarian Failure
NCT02389010 III Centro Nazionale Sangue|Italian National Cord Blood Network Platelet Gel From Cord Blood Diabetic Foot Ulcers
NCT00747708 II|III Barts & The London NHS Trust Bone Marrow Derived Adult Stem Chronic Heart Failure