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. Author manuscript; available in PMC: 2019 Jul 2.
Published in final edited form as: Anal Chem. 2018 Dec 18;91(1):757–767. doi: 10.1021/acs.analchem.8b03786

Table 1.

Summary of Applications of the Acoustofluidic Methods in Bioanalytical Chemistry

target of manipulation applications methodsa references
particle immunoagglutination assay standing BAW 32, 33
microparticle/cell concentration SSAW 34
BAW 35
nanoparticle/bacteria/ vesicle concentration SAW 36, 40, 41
standing wave + acoustic streaming 22
secondary acoustic radiation force 23, 37–39
cell focusing BAW 19, 42, 43
SSAW 44, 45, 51
cell sorting BAW 48
SSAW 46, 50–52
traveling SAW 47, 49
cell/particle separation BAW 17, 25, 53–56, 59
SSAW 18, 57
taSSAW 22, 60, 61
traveling SAW 21, 67
bacteria/vesicle separation BAW 58, 63, 65
SSAW 62, 64
taSSAW 66
fluid fluid mixing BAW 69
SAW 68, 70
oscillating bubble/sharp-edge 82, 83
pumping SAW 71–73
oscillating bubble/sharp-edge 80, 81
cell lysis and PCR SAW 20
nebulization SAW 74–79
vibrating sharp-edge 85
cell/microorganism rotation oscillating bubble/sharp-edge 84
a

Abbreviations: BAW, bulk acoustic wave; SAW, surface acoustic wave; SSAW, standing surface acoustic wave; taSSAW, tilted-angle standing surface acoustic wave.