Figure 3.

The effects of ketones on rotenone‐induced LTP impairment. This figure represents high frequency stimulation (HFS)‐induced LTP under the following conditions: (1) 50 nM rotenone (RTN) plus ketones (red symbols, n = 7 from 5 rats; 1 mM lithium acetoacetate plus 1 mM DL‐β‐hydroxybutyric acid sodium salt dissolved in incubation solution); (2) ketones alone (black symbols, n = 7 from 4 rats), and (3) rotenone alone (green symbols, n = 6 from 4 rats). These data showed that ketones significantly prevented rotenone‐induced LTP impairment.