Figure 1.

Effect of bupropion (150 mg twice daily) or placebo on the percentage of study participants who were in treatment and abstinence from methamphetamine through the end of the 12‐week study. In order for a week to be regarded as methamphetamine‐free, two or more methamphetamine‐free urine samples, with no methamphetamine‐positive samples, were required. Urine samples were regarded as methamphetamine‐free if they were below 300 ng/mL. This figure represents a reanalysis of data previously reported by Elkashef et al. [9]. Study participants (79 methamphetamine‐dependent individuals in the bupropion group and 72 in the placebo group) attended cognitive behavioral therapy counseling sessions and provided urine samples up to 3 times per week.