Table 5.
The effects of long‐term treatment with levamlodipine (Lev), bisoprolol (Bis), and their combination on hypertensive organ damages in spontaneously hypertensive rats. HW: heart weight; BW: body weight; AW: aorta weight, KW: kidney weight. *P < 0.05, **P < 0.01 versus Control
Dose (mg/kg) | Index | |||
---|---|---|---|---|
Lev | Bis | HW/BW | AW/Length | KW/BW |
0 | 0 | 3.55±0.26 | 2.53±0.36 | 6.02±0.27 |
1 | 0 | 3.24±0.16** | 2.11±0.36* | 6.59±0.75* |
0 | 0.25 | 3.33±0.17* | 2.18±0.15* | 6.46±0.51* |
1 | 0.25 | 3.11±0.25** | 2.01±0.34** | 6.55±0.51** |