Table 1.
Demographic and baseline characteristics of the patients
| Baseline parameters | IV rt‐PA (n = 70) | Untreated (n = 66) | P Value |
|---|---|---|---|
| Age, years, mean ± SD | 72.1 ± 10.8 | 74.1 ± 13.4 | 0.068 |
| Males | 45 (64.3%) | 36 (54.5%) | 0.247 |
| Hypertension | 51 (72.9%) | 37 (56.1%) | 0.042 |
| Diabetes | 11 (15.7%) | 9 (13.6%) | 0.733 |
| Atrial fibrillation | 26 (37.1%) | 32 (48.5%) | 0.181 |
| Hypercholesterolemia | 16 (22.9%) | 10 (15.2%) | 0.256 |
| History of stroke | 18 (25.7%) | 22 (33.3%) | 0.331 |
| Coronary artery disease | 16 (22.9%) | 7 (10.6%) | 0.057 |
| Time to treatment initiation | |||
| Mean ± SD | 196 ± 64.3 | 203 ± 59.2 | 0.485 |
| Median(range) | 190 (75–230) | 195 (60–270) | |
| NIHSS score | |||
| Mean ± SD | 20.1 ± 7.20 | 19.2 ± 6.28 | 0.442 |
| Median (range) | 20 (7–38) | 19 (8–36) | |
| GCS score | |||
| Mean ± SD | 9.50 ± 3.05 | 9.67 ± 2.54 | 0.728 |
| Median (range) | 10 (4–14) | 10 (5–14) | |
| ≤8 | 27 (38.6%) | 25 (37.9%) | 0.934 |
| 9–15 | 43 (61.4%) | 41 (62.1%) | |
| Circulation territory | 0.094 | ||
| TACI | 40 (57.1%) | 47 (71.2%) | |
| PACI | 18 (25.7%) | 15 (22.7%) | |
| POCI | 12 (17.1%) | 4 (6.1%) | |
| LACI | 0 | 0 | |
IV, intravenous; rt‐PA, reconstructive tissue plasminogen activator; SD, standard deviation; NIHSS, National Institutes of Health Stroke Scale; GCS, Glasgow Coma Scale; TACI, total anterior circulation infarct; PACI, partial anterior circulation infarct; POCI, posterior circulation infract; LACI, lacunar infarct.
Data are n (%) unless otherwise indicated.