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. 2013 May 22;19(9):659–666. doi: 10.1111/cns.12122

Figure 1.

Figure 1

The dose‐dependent effects of urinary trypsin inhibitor (UTI). Compared with other two doses, the dose of 50,000 U/kg UTI was the most effective on decreasing brain water content in left and right hemispheres (A) and neurological deficits (B) at 24 h after subarachnoid hemorrhage (SAH). n = 5,6,7,8,7 in sham, SAH + vehicle, SAH + 20,000, 50,000 and 100,000 U/kg UTI groups. At 24 h after SAH, 50,000 U/kg UTI markedly attenuated Evans blue content in left and right hemispheres (D), n = 6,7,6 in sham, SAH + vehicle, SAH + 50,000 U/kg UTI groups, although it could not significantly reduce the mortality (C). ※ P < 0.05 compared with the sham group; # P < 0.05 compared with the SAH + vehicle group.L.H, left hemisphere; R.H, right hemisphere; C, cerebellum; B.S, brain stem.