Figure 1.

Proliferation and migration of doublecortin (DCX)‐positive cells in the subventricular zone (SVZ) and dentate gyrus (DG). Representative immunofluorescence images of the SVZ (A–D) and DG (F–I) for DCX 4 weeks after ischemia demonstrated that the DCX‐positive signals area in the SVZ or the number of DCX‐positive cells in the DG were increased significantly in the ischemia group (B, G) compared with the sham group (A, F), and were much greater in the constraint‐induced movement therapy group (C, H) but were scarce in the irradiation group (D, I). Quantification of DCX‐positive signals areas in the SVZ (E) and DCX‐postive cells in the DG (J) showed that the differences between groups were significant. (*P < 0.05, **P < 0.01, n = 6, data are presented as means ± SEM, scale bar = 200 μm).