Table 2.

MiRNAs that are differentially expressed in ICH patients with or without hematoma enlargement

Serial number	Mature miRNA GSYM	P‐Valuea	Fold change	Chromosomal location
MicroRNAS with higher expression in hematoma enlargement cases
1	hsa‐miR‐522	0.007	2.491	Chromosome 19; NC_000019.9
2	hsa‐miR‐1290	0.004	2.453	Chromosome 1; NC_000001.10
3	hsa‐miR‐586	0.008	2.000	Chromosome 6; NC_000006.11
4	hsa‐miR‐29c	0.010	1.966	Chromosome 1; NC_000001.10
5	hsa‐miR‐100b	0.016	1.955	Chromosome 11; NC_000011.9
6	hsa‐miR‐130ab	0.007	1.895	Chromosome 11; NC_000011.9
7	hsa‐let‐7f‐2b	0.008	1.895	Chromosome X; NC_000023.10
8	hsa‐miR‐574‐5p	0.002	1.839	Chromosome 4; NC_000004.11
9	hsa‐miR‐29b‐1b	0.016	1.781	Chromosome 7; NC_000007.13
10	hsa‐miR‐122	0.008	1.764	Chromosome 18; NC_000018.9
11	hsa‐miR‐19ab	0.022	1.739	Chromosome 13; NC_000013.10
12	hsa‐miR‐29b	0.023	1.726	Chromosome 7; NC_000007.13
13	hsa‐miR‐545b	0.029	1.722	Chromosome X; NC_000023.10
14	hsa‐miR‐186b	0.026	1.664	Chromosome 1; NC_000001.10
15	hsa‐miR‐518c	0.041	1.635	Chromosome 19; NC_000019.9
16	hsa‐miR‐22	0.042	1.573	Chromosome 17; NC_000017.10
17	hsa‐miR‐542‐3p	0.045	1.545	Chromosome X; NC_000023.10
18	hsa‐miR‐369‐3p	0.033	1.516	Chromosome 14; NC_000014.8
19	hsa‐miR‐1294	0.042	1.432	Chromosome 5; NC_000005.9
MicroRNAS with lower expression in hematoma enlargement cases
20	hsa‐miR‐211	0.043	0.641	Chromosome 15; NC_000015.9
21	hsa‐miR‐365	0.039	0.626	Chromosome 16; NC_000016.9
22	hsa‐miR‐598	0.046	0.622	Chromosome 8; NC_000008.10
23	hsa‐miR‐325	0.049	0.621	Chromosome X; NC_000023.10
24	hsa‐miR‐454b	0.031	0.612	Chromosome 17; NC_000017.10
25	hsa‐miR‐573	0.047	0.587	Chromosome 4; NC_000004.11
26	hsa‐miR‐1265	0.013	0.577	Chromosome 10; NC_000010.10
27	hsa‐miR‐105b	0.036	0.551	Chromosome X; NC_000023.10
28	hsa‐miR‐1225‐5p	0.046	0.524	Chromosome 16; NC_000016.9
29	hsa‐miR‐1202	0.007	0.474	Chromosome 6; NC_000006.11
30	hsa‐miR‐1249	0.002	0.401	Chromosome 22; NC_000022.10

^a P‐values reported are the result of comparison analysis of microRNA expression levels from 32(14/18) ICH patients with or without HE.

^bIn the miRNA cloning study, investigators found that the same precursor could be transcripted from 5′ or 3′ respectively and generated two miRNA molecules. If the cloning research can determine the relative expression levels of the two molecules, a * sign was used to represent the secondary expression quantity molecule.