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. 2019 Apr 19;15(4):e1006760. doi: 10.1371/journal.pcbi.1006760

Table 6. Metabolites associated with NAFLD phenotypes.

This provides a summary of key metabolites associated with the four phenotypes and their corresponding references. Metabolites are taken from the mouse metabolic model of Sigurdsson and colleagues [14]. Production of each of these metabolites represents a metabolic task (MT).

Metabolites Phenotype Reference
Diacylglycerol, phosphatidylethanolamine, cholesteryl esters, triacylglycerol, hexadecanoate, cholesterol, phosphatidic acid, phosphatidylinositol, phosphatidylserine Lipid droplets [42, 43, 45]
Ceramide Inflammation [30, 45, 46]
Alanine, glutamine, ceramide Apoptosis [47]
Superoxide anion, hydrogen peroxide Oxidative stress [44]