Table 6. Metabolites associated with NAFLD phenotypes.
This provides a summary of key metabolites associated with the four phenotypes and their corresponding references. Metabolites are taken from the mouse metabolic model of Sigurdsson and colleagues [14]. Production of each of these metabolites represents a metabolic task (MT).
Metabolites | Phenotype | Reference |
---|---|---|
Diacylglycerol, phosphatidylethanolamine, cholesteryl esters, triacylglycerol, hexadecanoate, cholesterol, phosphatidic acid, phosphatidylinositol, phosphatidylserine | Lipid droplets | [42, 43, 45] |
Ceramide | Inflammation | [30, 45, 46] |
Alanine, glutamine, ceramide | Apoptosis | [47] |
Superoxide anion, hydrogen peroxide | Oxidative stress | [44] |