Table 1.

Effects of nitric oxide drugs and nicotine on the firing pattern of SNc dopaminergic neurons

Treatment	Δburst
Vehicle	0.83 ± 1.61
l‐NAME (i.p.)	−0.14 ± 2.9
l‐NAME (iontophoresis)	−0.04 ± 1.6
7‐NI (i.p.)	−5.70 ± 3.1
l‐ARG (i.p.)	−2.33 ± 6.5
l‐ARG (iontophoresis)	−0.48 ± 1.6
MOL (i.p.)	1.62 ± 1.5
Nicotine (i.v.)	20.41 ± 7.51a
Nicotine +l‐NAME (i.v.+ i.p.)	9.9 ± 7.01b
Nicotine + 7‐NI (i.v.+ i.p.)	4.9 ± 2.6b
Nicotine +l‐NAME + MOL (i.v.+ i.p.)	15.2 ± 6.68a
Nicotine +7‐NI + MOL (i.v.+ i.p.)	9.46 ± 11.01b

^a P < 0.05 compared with vehicle group, ^b P < 0.05 compared to nicotine (Mann‐Whitney U test).