Table 1.
Examples of the neuroprotective effects of lithium in neuronal cell cultures or models for studies of specific aspects of different experimental neuropathological processes
| Neuropathological process (disorder) | Neurotoxin | Cell/tissue culture/experimental model | References |
|---|---|---|---|
| Alzheimer disease | Amyloid beta‐peptide | Hippocampal neurons and PC12 cells | [4] |
| Transgenic mouse model of AD hippocampus | [7, 20, 25] | ||
| Amyotrophic lateral sclerosis | Mouse model | [3, 6] | |
| Parkinson disease | MPTP | Rat treatment | [64] |
| Huntington disease | Huntingtin overexpression | Caenorhabditis elegans | [68] |
| 3‐Nitropropionic acid | Rat treatment | [28] | |
| Cerebral ischemia | Model of ischemia | Rat | [81] |
| Epilepsy | Kainic acid | Rat | [76] |
| Aging | C. elegans | [86] | |
| SAMP‐8 | [40, 90] |