Figure 1.

Effects of PPE and TFs treatment on mouse body weights, food and water consumption. Structures of green tea polyphenols (a) and theaflavins (b); effects of PPE and TFs treatment on mouse body weights (c), food consumption (d) and water consumption (e). For green tea polyphenols – Epigallocatechin 3-gallate (EGCG): R1=galloyl, R2= OH; Epigallocatechin (EGC): R1 = H, R2 = OH; Epicatechin 3-gallate: R1 = galloyl, R2 = H; and Epicatechin: R1= R2= H. For theaflavins – Theaflavin (TF): R1 = R2 = H; TF-3-gallate: R1 = galloyl, R2 = H; TF-3‘-gallate: R1 = H, R2 = galloyl and TF-3,3‘digallate: R1 = R2 = galloyl. Body weight (n=12 mice) and food or water consumption (n=3 cages) were measured 3 times per week. For clarity, only the weekly data are shown as mean ± S.E. ^a,b indicate difference among groups by ANOVA (p < 0.05).