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. 2015 Aug 27;2015(8):CD011054. doi: 10.1002/14651858.CD011054.pub2

Sidney 1998.

Methods Case‐control study
Participants 271 cases/993 controls
Aged 18 to 44 years
Interventions Combined oral contraception: current use, past use, none use, norethindrone, norgestrel, < 50 µg oestrogen, ≥ 50 µg oestrogen
Outcomes Myocardial infarction
Events: current use 12/87, past use 214/769, none use 41/135, norethindrone 8/52, norgestrel 3/24, < 50 µg oestrogen 9/78, > 50 µg oestrogen 2/5
Notes USA
Risk of bias
Bias Authors' judgement Support for judgement
Exposure ascertainment High risk COC use not objectively confirmed.
Outcome assessment High risk Myocardial infarction not objectively confirmed.
Follow‐up Unclear risk Not applicable as this was a case‐control study.
Source population Low risk Controls from the same source population as the cases.