Ghods 1995.

Methods	4‐week dietary washout period 12‐week before and after trial
Participants	10 men and women with nephrotic syndrome and hypercholesterolaemia TC > 240 mg/dL (6.21 mmol/L) LDL‐C > 160 mg/dL (4.14 mmol/L) exclusion criteria: liver disease, participants, 18 years, pregnancy potential Fluvastatin 20 twice daily baseline TC : 9.982 mmol/L (386 mg/dL) Fluvastatin 20 twice daily baseline LDL‐C : 6.025 mmol/L (233 mg/dL) Fluvastatin 20 twice daily baseline HDL‐C : 1.32 mmol/L (51 mg/dL) Fluvastatin 20 twice daily baseline triglycerides: 5.837 mmol/L (517 mg/dL)
Interventions	Fluvastatin 20 twice daily
Outcomes	per cent change from baseline at 4‐12 weeks of serum TC, LDL‐C, HDL‐C, and triglycerides
Source of Funding	unknown
Notes	SDs were imputed by the method of Furukawa 2006
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Controlled before and after design
Allocation concealment (selection bias)	High risk	Controlled before and after design
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Lipid parameter measurements unlikely influenced by lack of blinding
Blinding of outcome assessment (detection bias) LDL‐cholesterol	Low risk	Lipid parameters were measured in a remote laboratory
Blinding of outcome assessment (detection bias) WDAEs	High risk	No comparison possible
Incomplete outcome data (attrition bias) All outcomes	Low risk	All participants were included in the efficacy analysis
Selective reporting (reporting bias)	Low risk	LDL‐C outcome was reported
Other bias	Unclear risk	Source of funding not reported