Comparison 3. Ibuprofen 400 mg + oxycodone 5 mg versus oxycodone 5 mg.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Participants with ≥50% pain relief at 6 hours	2	471	Risk Ratio (M‐H, Fixed, 95% CI)	2.46 [1.75, 3.46]
2 Participants using rescue medication within 6 hours	2	471	Risk Ratio (M‐H, Fixed, 95% CI)	0.53 [0.46, 0.62]
3 Participants with any adverse event over 6 hours	2	471	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.58, 1.04]