Study	Reason for exclusion
Aksamit 2016	Wrong comparator. The trial compares inhaled ciprofloxacin to placebo.
Alder 2011	Wrong comparator. The trial compares inhaled ciprofloxacin to placebo.
Antoniu 2011	Wrong comparator. The trial compares inhaled gentamicin to placebo.
Bilton 2006	Wrong intervention. The trial compares the addition of inhaled tobramycin to ciprofloxacin versus ciprofloxacin alone.
Chalmers 2012	Not a randomised controlled trial. The study sought to investigate the impact of long‐ and short‐term antibiotic treatment on inflammation.
Fiel 2000	Wrong comparator. The trial compares inhaled tobramycin to placebo.
Flume 2013	Wrong comparator. The trial compares inhaled aztreonam to placebo.
Hampel 2011	Wrong comparator. The trial compares inhaled ciprofloxacin to placebo.
Labiris 1999	Wrong comparator. The trial compared inhaled and nebulised gentamicin to intravenous gentamicin in a triple cross‐over design.
Ledson 2000	Letter to editor regarding "n of 1" trial of inhaled taurolidine versus placebo
Murray 2009	Wrong comparator. The trial compares inhaled gentamicin to placebo.
NCT00749866 2008	Wrong comparator. The trial compares inhaled gentamicin to placebo.
NCT01313624 2011	Wrong comparator. The trial compares inhaled aztreonam to placebo.
NCT01677403 2012	Wrong comparator. The trial compares inhaled tobramycin to placebo.
O'Donnell 1999	Wrong comparator. The trial compares inhaled tobramycin to placebo.
O'Donnell 2016	Wrong comparator. The trial compares inhaled ciprofloxacin to placebo.
Orriols 1999	Wrong comparator. The trial compares inhaled ceftazidime and tobramycin to usual care.
Santiveri 1995	Wrong comparator. The trial compares addition of inhaled antibiotics to intravenous antibiotics versus intravenous antibiotics alone.
Serisier 2012	Letter to editor regarding trial of inhaled gentamicin compares to placebo
Shrewsbury 2004	Wrong intervention. The trial compares the addition of inhaled tobramycin to ciprofloxacin to ciprofloxacin alone.
Soyza 2015	Wrong comparator. The trial compares inhaled ciprofloxacin to placebo.
Tabernero 2012	Wrong comparator. The trial compares inhaled colistin to usual care.
Terpstra 2016	Wrong comparator. The trial compares two different doses of inhaled tobramycin to placebo.
Twiss 2008	Wrong comparator. The trial compares inhaled gentamicin to placebo.
Twiss 2009	Wrong comparator. The trial compares inhaled gentamicin to placebo.
Wilson 2011	Wrong comparator. The trial compares inhaled ciprofloxacin to placebo.
Wong 2004	Wrong intervention and wrong comparator. Trial compares intravenous followed by oral antibiotics for an acute exacerbation of bronchiectasis, versus a full intravenous course of antibiotics.