Sand 2001.

Methods	Prospective, randomised, controlled trial Participant selection by computer‐generated random number tables 12‐Month follow‐up
Participants	161 women enrolled in trial Anterior/posterior colporrhaphy with polyglactin 910 mesh (80) Anterior/posterior colporrhaphy without polyglactin 910 mesh (80) (1 woman excluded) 17 lost to follow‐up at 52 months Inclusion: cystocele protruding to or beyond the hymenal ring in the standing position while coughing or straining, regardless of other concurrent prolapse. Participants had to be > 18 years old, ambulatory, and willing to comply with return visits. Exclusion: pregnant or contemplating pregnancy in the next 12 months. Had only an anterior enterocele or only a paravaginal defect with no need for central cystocele repair at the time of reconstructive surgery Patients seen at 2, 6, 12, and 52 weeks after surgery
Interventions	Anterior/posterior colporrhaphy with polyglactin 910 mesh (80) Anterior/posterior colporrhaphy without polyglactin 910 mesh (80) (1 woman excluded)
Outcomes	Recurrent posterior vaginal wall prolapse (objective failure)
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated random number tables
Allocation concealment (selection bias)	Low risk	Sequentially numbered, opaque, sealed envelopes
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not stated
Blinding of outcome assessment (detection bias) All outcomes	High risk	Examiner not blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	17 lost to follow‐up at 52 months (11%). Not stated in study to which groups these were assigned, but it is stated that loss to follow‐up was not significantly different between the 2 groups
Selective reporting (reporting bias)	Unclear risk	Reported on 1 of this review's primary outcomes, protocol not found
Other bias	Unclear risk	Not stated Concomitant procedure was anterior vaginal repair; same numbers in both comparison groups had concomitant procedures.