| Trial name or title |
A prospective cohort study for propranolol treatment in retinopathy of prematurity. |
| Methods |
Randomised, placebo‐controlled trial. |
| Participants |
Preterm newborns (birth weight less than 1500 grams) with stage 1 or 2 ROP in zone II or III without plus. |
| Interventions |
Propranolol ophthalmic solution (0.2%) 0.25 mg/kg/d. 3 microdrops propranolol solution or placebo in each eye 4 times daily until complete retinal vascularisation, but no more than 90 days. |
| Outcomes |
Primary outcomes: ROP progression; rate of surgical treatment; adverse effects, steady state plasma concentrations of propranolol. |
| Starting date |
2017 |
| Contact information |
chuannie@sina.com |
| Notes |
Phase 2 interventional study |
