Skip to main content
. 2018 May 9;2018(5):CD004945. doi: 10.1002/14651858.CD004945.pub4

Herabutya 1992.

Methods RCT
Participants Number of women randomised: 108
 Setting: Bangkok, Thailand
Inclusion criteria
  • Certain dates

  • Low risk

  • GA at intervention: 42 completed weeks (immediately after)


Exclusion criteria
  • Women with Bishop scores of > 6 were judged to have a favourable cervix and were excluded from the study


State of cervix: unfavourable cervix (Bishop score 6 or less)
Interventions Induction group (n = 57): PGE2 intracervical, repeated after 6 hours, AROM and oxytocin on day 2 according to contractions
versus
 Expectant management group (n = 51): a) NST between 42 and 43 completed weeks. 2) NST between 43 and 44 completed weeks; women underwent IOL if there were abnormalities in antepartum fetal testing as non‐reactive NST, or variable decelerations on NST or if Bishop score > 6 on reaching 44 completed weeks' gestation.
Outcomes Mother: length of first stage of labour; mode of birth; cephalopelvic disproportion; fetal distress
Baby: birthweight; meconium staining; Apgar score < 7 at 1 min; Apgar score < 7 at 5 min; intubation required; admission to special care baby unit; perinatal death
Notes Funding: Ramathibodi Hospital Research Fund Grant 1988
Declaration of interests: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk The method of sequence generation was not reported.
Allocation concealment (selection bias) Unclear risk The method of allocation concealment was not reported.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Blinding was not feasible.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Blinded outcome assessment was not mentioned.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No apparent losses to follow‐up or exclusions.
Selective reporting (reporting bias) Unclear risk No outcomes were pre‐specified in the methods; no access to trial protocol to further assess selective reporting.
Other bias Low risk Appears to be free of other bias.