Skip to main content
. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):799–809. doi: 10.1161/ATVBAHA.118.312328

Figure 2: AB023 reduces platelet-rich thrombus growth in a primate thrombosis model.

Figure 2:

Effect of AB023 (1.0 mg/kg, IV) on platelet (A-C) deposition on (A) collagen-coated (4 mm diameter, 2 cm long) vascular grafts and (B) 10 cm downstream of the collagen-coated graft (“tail”). (C) Platelet deposition in both the graft + tail combined. (D-F) Fibrin deposition within the collagen graft (D), tail (E) and graft + tail combined (F) in control treated (black bar) and after AB023 treatment. Values are mean ± SEM, n = 4 experiments/ group in 4 animals. *p<0.05, **p<0.01, ***p<0.001 vs. control. Each animal underwent a control experiment followed by AB023 experiment.