Table 3.

Adjusted total costs based on area of spending

	Low cost	High cost	Total		Range		Ratio
Centers	N=8	N=16	N=24	p-value*	Minimum	Maximum	Max/Min
Patients	N=705 (32.7%)	N=1451 (67.3%)	N=2156
Pharmacy costs	$32,067 ($24,746 – $46,996)	$57,851 ($39,553 – $92,312)	$47,561 ($31,788 – $76,439)	<0.001	$25,014	$183,088	7.3
Lab costs	$25,506 ($18,295 – $38,999)	$46,405 ($30,969 – $76,515)	$38,406 ($24,860 – $64,510)	<0.001	$11,883	$86,478	7.3
Imaging costs	$7,753 ($4,534 – $12,607)	$15,739 ($9,579 – $25,113)	$12,497 ($6,924 – $21,580)	<0.001	$2,419	$31,581	13.1
Supply costs	$12,982 ($7,166 – $26,101)	$26,715 ($14,278 – $51,650)	$21,324 ($10,985 – $43,379)	<0.001	$3,530	$55,876	15.8
Clinical costs	$154,025 ($113,877 – $194,001)	$237,408 ($160,270 – $313,364)	$199,927 ($136,490 – $275,670)	<0.001	$78,569	$613,638	7.8
Other costs	$113,694 ($79,976 – $169,980)	$180,973 ($119,708 – $266,289)	$156,859 ($102,020 – $241,452)	<0.001	$76,712	$311,475	4.1

^*p-values from the Wilcoxon rank sum test

Cost expressed as median (interquartile range), inflated to 2016 dollars